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Mol Metab 2014;4:118-31.ArticlePubMedPMC 89

moderate renal impairment (eGFR 30-45 ml/min) has been observed to increase plasma levels of sitagliptin 2-fold, and severe renal impairment can increase plasma levels 4-fold

In the gastrointestinal tract, GLP-1 binding to its receptors delays gastric emptying, reduce appetite, and increase satiety [11]

[DOI] [PMC free article] [PubMed] [Google Scholar] 16.ElSayed N

January 22, 2024
