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The GLP1R/GIPR dual agonist NNC 00902746 (Novo Nordisk) significantly improved hemoglobin A1c (A1c) in T2DM (a reduction of 0.96% vs placebo) over a 12-week period, accompanied by a reduction in body weight

It works by copying the actions of two natural hormones in the bodyGIP and GLP-1

Contact your GP if you experience significant weakness affecting daily activities, difficulty climbing stairs or rising from chairs, unexplained falls, rapid weight loss exceeding 12 kg weekly, or severe nausea preventing adequate food intake

[DOI] [PMC free article] [PubMed] [Google Scholar] 3.Surampudi P, Swerdloff RS, Wang C
