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She showed that infusion of both GLP-1 and exendin-4 prevented glucose-induced pancreatic blood flow redistribution into the islets, an effect that was not abolished by blocking NO formation [116]

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Marketed under the brand name Mounjaro, tirzepatide represents a significant advancement in diabetes pharmacotherapy as the first dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist

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