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Description
It affects 1923% of adults at higher doses in clinical trials, peaking during dose-escalation weeks, and runs roughly 23 times higher than placebo across every dose group
This means it should not be used by patients with a personal or family history of MTC or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

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The review notes that the drug can improve brain leptin sensitivity, potentially breaking the connection between obesity and AD

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