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4, the three most frequently reported SOC categories were "Gastrointestinal disorders," "General disorders and administration site conditions," and "Investigations." Notably, while "Injury, poisoning, and procedural complications" and "Nervous system disorders" demonstrated higher reporting frequencies compared to other SOCs, these associations did not reach statistical significance in our analysis, suggesting potential reporting bias or confounding factors that warrant further investigation

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To view a copy of this licence, visit About this article Cite this article Avogaro, A., Neccia, M., Delfini, M