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Think of BMR as the energy your body needs just to stay alivebreathing, keeping warm, and all that good stuff
But, as we all know, its tough to break old habits
These approaches do not account for the fact that complex chronic diseases are driven by multiple distinct biological mechanisms, and that patients have different genetic and comorbidity backgrounds meaning they will respond differently to modulation of GLP-1 pathways

The treatment effect reflected a reduction in a sustained decline in eGFR of 50%, progression to kidney failure and CV death
Their role as monotherapy has diminished in North America
