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Type 2 diabetes and risk of hospital admission or death for chronic liver diseases

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Further, the -helix fractions ( f a ) of SR18 calculated at 222 were found to be in the range of 0.034 in 1X PBS, 0.12 in 20% TFE, 0.22 in 20% HFIP, and 0.17 in 30 mM SDS (Supplementary Table S2), which is noted to be comparable with the reported value of 0.027 for semaglutide (Hamley et al., 2025)

Indeed, kidney secondary outcomes from CVOTs showed a decrease in albuminuria and in events related to decreased GFR when GLP-1 RAs were tested for T2DM (enrolling a majority of participants with overweight/obesity) or overweight/obesity without T2DM, as discussed below [26, 41, 48] (Table 3)

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