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Andrew Dillin, quoted in this New York Times article on rapamycin, thinks not: Why take risks with unproven benefits? he told The Times

In humans, GLP1 meds were shown to reduce activity in anticipation areas of the brain (like the insula) and increase activity when actually eating , helping curb cravings

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This would be a huge step towards transitioning the medical system away from using opioids for chronic pain, which would reduce harmful side effects and prevent new addictions in patients and via diversion

moderate weight loss (25 kg)