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Why an existing medication may be our best hope to prevent dementia

Both receptors influence glucose metabolism

This striking difference is probably a result of the fact that agonists bind class B GPCRs predominantly at their large extracellular N-termini and TM1 helices, whereas class A GPCRs mainly interact with agonists deep inside the TM helical bundle and/or at the extracellular loops (ECLs) [15]

neither withdrawal was due to any adverse events (AEs)
