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Similarly, the 90% CIs for the estimated ratios of C max for ethinylestradiol and levonorgestrel were within the pre-specified interval (Fig
PMID: 8538742
Ongoing monitoring includes weekly check-ins during the first month, then biweekly assessments during dose escalation
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Circumventing the then-standard Boc/Bzl protecting group paradigm, these choices made it possible to avoid using the strong acid anhydrous hydrogen fluoride (HF) for final cleavage of the peptide from the solid support
