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FDA=US Food and Drug Administration
Additionally, pharmacovigilance analyses using the FDA Adverse Event Reporting System (FAERS) noted an increased number of thyroid-related reports, including hyperplasia and neoplasms, associated with GLP-1 receptor agonists
Mechanistically, L-tryptophan upregulated the expression of GLP-1related genes (e.g., Gcg and Pcsk1 ) in intestinal L cells, further promoting GLP-1 production ( In contrast, some postbiotics may suppress GLP-1 signaling
doi: 10.3389/fendo.2021.645563 25 HughesSNeumillerJJ
Id called it early for the year on policy analysis other than the CMS ACCESS model
