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The dosage should be individually titrated every few days on the basis of self-monitored blood glucose levels
By contrast, peptides such as PYY and apelin were discontinued primarily due to formulation limitations or tolerability at supraphysiologic dosespharmacologic rather than biological failuresand therefore meet criteria for re-evaluation
MicroRNA-194: a novel regulator of glucagon-like peptide-1 synthesis in intestinal L cells
BMJ 388:e080679
In contrast, fatty acid acylation enhances binding affinity to plasma albumin by incorporating lipophilic chains (commonly C16 or C18) into the peptide structure [191]
