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If IGF-1 remains flat or declines while on sermorelin, the issue is usually one of three things: insufficient dosing, poor injection timing (too close to meals, which blunts the GH pulse), or interference from another medication

Weight Loss Goals: How much weight do you need or want to lose for your health

Hitting the 1.2 to 1.6 g/kg target that clinical weight-loss guidelines recommend keeps more of your weight coming off fat rather than lean tissue, which softens how pronounced the facial change becomes

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The patch is worn on the skin and provides a consistent hormone dose, typically changed once or twice a week