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Maximizing GLP-1 dosing alone typically produces 15-24% weight loss, which is substantial

10.1371/journal.pone.0061965 59 SirohiS.SchurdakJ

Recent studies using GLP1R/GIPR dual agonists, especially the SURPASS clinical trials, have revealed beneficial effects of GIP activation when used in conjunction with GLP-1RAs

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Epac proteins: multi-purpose cAMP targets
