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Understanding which patients are candidates for GLP-1RAs treatment will be key, according to Lorenzo Leggio, MD, PhD, clinical director of the National Institute on Drug Abuse

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doi: 10.1016/j.pneurobio.2010.07.003 [DOI] [PubMed] [Google Scholar] 25

"Due to the progressive nature of type 2 diabetes, were often having to intensify therapy," Billings said

On this basis, women are advised to avoid pregnancy until five half-lives of the drug have elapsed to allow adequate drug wash-out, and to advocate for trials that specifically include women planning pregnancy