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Description
Bile acid changes after gallbladder removal can affect GLP-1 tolerability and gastrointestinal side effects

Together, these medications act on the brains hunger and reward centers, making it easier to manage portions, resist cravings, and stay consistent with lifestyle changes.

New therapies such as resmetirom and semaglutide mark a shift in treatment

In conclusion, the benefits of GLP-1RAs in MASLD are promising, and background therapy involving metabolic modulation may represent one of the future therapeutic paradigms.

Survodutide (BI 456906), a novel dual GLP-1 and glucagon receptor agonist, demonstrated weight loss of up to 18.7% over 46 weeks in overweight or obese people
