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In SURMOUNT-5, which directly compared the two medications, Mounjaro 15 mg produced 20.2% weight loss, while Wegovy 2.4 mg produced 13.7% over 72 weeks

In the peripheral nervous system, both drugs affect the cardiac function, via SNS and parasympathetic nervous system (PNS)

Eligible Part D members pay $50 a month for a covered GLP-1 prescribed for weight management Claims and prior authorization go through a central processor, not the patient's regular Part D plan The $50 copay does not count toward the Part D deductible or annual out-of-pocket cap Patients already on a GLP-1 through Part D for diabetes, cardiovascular risk, sleep apnea, or MASH stay on their existing path Eligibility depends on BMI thresholds and conditions such as high blood pressure, heart failure, chronic kidney disease, prediabetes, or a history of cardiovascular disease

Learn more about potential side effects Your Ro-affiliated provider will walk you through the side effects patients report most often: Nausea Vomiting Upset stomach Stomach pains Constipation Diarrhea Learn more about safety information, including serious warnings: ro.co/safety/ Meet our expert Feel like youre doing everything right, but the weight still doesnt budge

Monitor the tissue depth at each site periodically