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and promotion of muscle mitochondria biogenesis.The potential for GLP-1R agonists to improve muscle function and architecture underscores the need for large randomized controlled, clinically comparative trials of GLP-1R agonists in patients with IIM.

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Interestingly, semaglutide tends to cause fewer gastrointestinal side effects compared to other GLP-1 agonists

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In this guideline, we update the pharmacotherapy recommendations in the 2020 Canadian clinical practice ...

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