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Description
Liraglutide, a once-daily human GLP-1 analogue, added to a sulphonylurea over 26 weeks produces greater improvements in glycaemic and weight control compared with adding rosiglitazone or placebo in subjects with type 2 diabetes (LEAD-1 SU)

In the context of breast reconstruction, GLP-1 RAs may help broaden eligibility for autologous procedures such as DIEP flap reconstruction

Verdile G, Keane KN, Cruzat VF, et al

This was a landmark moment because it represented global recognition of GLP-1 medications as a legitimate long-term treatment for obesity rather than a temporary or supplementary intervention
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