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Thus, the differential regulation of the oxidative phosphorylation pathway could reflect improved insulin sensitivity in response to increased insulin-driven ROS production, which has been suggested to inhibit food intake via the hypothalamus (55, 56)

However, it is associated with an increased risk of gastrointestinal side effects such as nausea, vomiting, and diarrhea, which often leads to treatment discontinuation

2021 Nov 25;22(23):12754

[DOI] [PMC free article] [PubMed] [Google Scholar] 103.Moore, K

112 In addition, the development of a novel T7-SN-38 PDC using the affinity of HAIYPRH (T7) peptide to TfR overexpressed on blood-brain barrier and glioma cells has also been recently reported