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Br J Pharmacol 179(4):727742 Cheng M, Ren L, Jia X, Wang J, Cong B (2024) Understanding the action mechanisms of Metformin in the Gastrointestinal tract

Clinical research shows both can produce meaningful weight loss, but individual response varies based on genetics, stomach acid levels, and how your body processes the compound

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Unlike some medications that lose effectiveness over time, incretin-based therapies maintain efficacy in multi-year studies
