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When GLP-1 drugs may be appropriate for lipoedema With all of the above said, there are circumstances where GLP-1 drugs may be a reasonable consideration for women with lipoedema: When prediabetes or type 2 diabetes is present and not adequately controlled through nutrition alone When chronic stress and cortisol dysregulation are significantly impairing metabolic function despite a well-structured nutrition protocol When these decisions are made collaboratively with a medical team that understands lipoedema and is actively monitoring muscle mass, bone health, nutritional status, and mental health In all cases, a low-inflammatory, nutritionally balanced eating approach remains essential alongside the medication GLP-1 drugs are not a replacement for good nutrition

In terms of stomachache, 4 studies (with 229 subjects from each of the groups) were included for analysis

Effects of exenatide on measures of beta-cell function after 3 years in metformin-treated patients with type 2 diabetes

These improvements may reflect combined metabolic, immune, and inflammatory effects rather than a single mechanism

A vague sense of feeling satisfied with smaller portions