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Beyond 12 hours at room temperature, semaglutide should be considered compromised and discarded

Key Takeaways GLP-1 medication starts showing initial effects and early signs of appetite reduction and improved blood sugar control within the first few weeks

Impact on the Autonomic Nervous System The hormones that tirzepatide mimics do more than just regulate hunger

Losing weight lowers the risk of high blood pressure, type 2 diabetes, high blood pressure, heart disease, and other serious and often life-threatening health issues

DISCUSSION We leveraged longitudinal measurements, wearable technology, and causal inference to characterize cardiovascular and behavioral responses during the initial 12 wk of GLP-1 RA therapy