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By understanding and managing the side effects, patients can maximize the benefits of semaglutide and bupropion while minimizing discomfort

The safety profile is favorable

Overall, 12.7% of users were newly diagnosed with a nutritional deficiency at 6 months and over 22% by 12 months

15 The SFRP2/DPP4 fibroblast subpopulation serves as the progenitor for fibrogenic fibroblasts in SSc skin, and DPP4-induced NF-kB and SMAD signaling via PAR2 activation leads to dermal fibroblast activation