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This yielded a risk difference of 0.3% (95% CI 0.6% to 0.04%) and an HR of 0.87 (95% CI 0.75 to 1.01) (Fig

GLP-1RAs also reduced several other markers of oxidative stress in rodent stroke models, such as blood and brain ROS counts, blood levels of derivatives of reactive oxygen metabolites (d-ROMs), and brain levels of dihydroethidium, a marker of ROS production [66, 87]

They may be prescribed only when an FDA-approved alternative is unavailable or clinically inappropriate for an individual patient, as permitted by law

Gen Z was the most likely (36%)

In this analysis, once-weekly GLP-1 RAs were associated with an 11% lower risk of non-adherence compared with once-daily GLP-1 RAs (risk ratio: 0.89