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Subsequently, PKA activity can augment the release of neurotransmitters into the synapse, facilitating long-term potentiation (LTP) and promoting cAMP-response element binding protein (CREB) phosphorylation, supporting cell growth/survival as well as synaptic plasticity [31, 33]

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The authors suggest this may reflect a dysregulated incretin system that was not overcome by pharmacological doses of the drugs within six months

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Gyms, wearables, activewear, and healthtech are all benefiting as GLP-1s serve as an entry point for a new wave of wellness consumers