retatrutide triple agonist glp-1 gip glucagon phase 2 obesity Retatrutide: The GLP-1/GIP/Glucagon Triple-Agonist Guide to Weight Loss, Appetite Control & Metabolic Reset Diagram showing the mechanism of
Description
Reduced appetite is the intended effect, though it sometimes feels too extreme
GLP-1 and GIP control blood glucose levels by stimulating insulin secretion by pancreatic -cells while inhibiting glucagon secretion, increasing pancreatic -cell proliferation, and decreasing their apoptosis [3,4,5,6,7,8]
doi: 10.1074/jbc.M111.276808
doi:10.2337/dc11-s231 Jensterle M, Rizzo M, Haluzk M, Jane A
SmartPill, a novel ambulatory diagnostic test for measuring gastric emptying in health and disease
