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A single GLP-1 agonist, semaglutide produces approximately 15-17% body weight reduction, which is significantly better than phentermine but somewhat less than tirzepatide maximum doses

Studies shows that caffeine can improve muscle contractions, reduce fatigue, and improve sports performance

Other common side effects include: Decreased appetite, which is partly the point but can become excessive Fatigue, especially in the first few weeks Injection site reactions like redness or mild swelling Belching and bloating Heartburn and acid reflux These are not rare edge cases

GLP-1 reduces intestinal lymph flow, triglyceride absorption, and apolipoprotein production in rats

These effects were particularly strong during the initial phase of treatment, and sustained suppression of food intake and weight loss continued throughout the three-week evaluation period