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56 After 3 years, the primary composite outcome (nonfatal myocardial infarction, nonfatal stroke, or CV death) occurred in fewer patients assigned to the SGLT2-I versus placebo (10.5% vs 12.1%

However, there are reasons to be optimistic about the future

Direct comparison trials between the two are still running

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6 GLP-1 RAs exhibit significant nephroprotective effects, including reducing albuminuria, improving renal haemodynamics and attenuating oxidative stress and inflammation in the kidneys