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Rose, 1

Non-peptidomimetic inhibitors are structurally diverse but common key interactions with DPP4 can be observed

NICE does not currently recommend any treatment specifically targeting obesity-related inflammation as a standalone indication

The USPTO allows filing a continuing patent application (Continuation, Continuation-in-part and divisional) which claims the priority date of the parent application and therefore does not have a term starting from its filing date but from the earliest filing date of the parent application

Peptide YY and other satiety peptides demonstrate clear physiological roles, with early failures attributable to rapid exposure and intolerance rather than to a lack of efficacy, again favoring re-evaluation
