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Although GIP(1-30)NH2 is as potent as GIP(1-42) in GIPR binding and cAMP production [228], and to stimulate insulin secretion in either the perfused mouse pancreas [109], rat islet insulinoma RIN1046-38 cells [229], mouse pancreatic TC-3 cells [229], and healthy human subjects [230], its circulating levels are only 13 pmol/l, which is 15 fold lower than the fasting GIP(1-42) serum concentration [226,231]

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doi:10.1097/MCO.0b013e328365b9be 101

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