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In a double blinded placebo-controlled study, weekly injections of retatrutide (12 mg) in obese patients, in conjunction with lifestyle changes, showed average weight decreases of 22.1% over placebo patients after 48 weeks

Results from this study could help expand the understanding of the therapeutic potential of a GLP-1RA for the treatment of asthma, within the context of obesity, by evaluating the direct impact it has on the airway and offering a therapeutic alternative for patients that no longer respond to traditional asthma treatment

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doi: 10.1016/j.ejphar.2013.03.041 349 HrubyVJ

The primary reason a researcher might transition focus from tirzepatide to retatrutide is to investigate the impacts of glucagon agonism on energy expenditure and liver fat
