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Additionally, there was GLP1 RA expression in tumor cells and infiltrating immune cells in human TNBC specimens, suggesting potential immunomodulatory effects that can impact treatment response

GLP-1 is an incretin molecule mainly secreted by enteroendocrine L cells, alpha cells, and the central nervous system

For someone losing 50 lbs on Retatrutide, this could mean 12-20 lbs of that loss is muscle
Clinical trials consistently show average weight losses of 1521% of baseline body weight over 72 weeks, making weight gain an unexpected response that warrants investigation

Qiao C, Dang T, Zhou Y et al
