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Ethics declarations Conflict of interest Exendin-4-Fc has been developed as a drug (under name JY09) for type 2 diabetes and a Phase II clinical trial (#CTR20192166) is being carried out in China

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Table 1: Abbreviation: F/B ratio ( Firmicutes to Bacteroidetes ratio) Table 2: In conclusion, using gut flora with antidiabetic medications may be a compelling way to enhance the results of T2DM