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Primary cultured lung fibroblasts treated with TGF-1 combined with IL-1 (TGF-1+IL-1) were used to explore the specific effects of liraglutide, MCC950, and 3PO on fibroblast activation in vitro

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Methods We selected individuals aged 45 years and older already treated with metformin living in Lombardy, Italy, and then split them into two groups if they initiated GLP-1 RAs or other antidiabetic drugs, between 2019 and 2021