glp-1 for addiction What to know about how medications might fight GLP-1 and Addiction: Clinical Trials
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The dual mechanism provides metabolic advantages, including potentially greater weight loss and metabolic improvement , without adding thyroid-specific concerns

(03:43): So you'd have efficient lowering of glucose through a dual mechanism with increasing insulin, lowering glucagon, and then it was safe because there wasn't this hypoglycemia you get from insulin

E.et al
In fact, only a modest improvement in insulin resistance was consistently detected in PWA mice following treatment with metformin, as reflected by a moderately reduced HOMA-IR index
