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Tirzepatide creates a window of reduced appetite and improved metabolic function

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This extended period contributes to the medications excellent tolerability profile and reduces early discontinuation due to GI symptoms

As many as 70% (perhaps more) people with PCOS have a degree of insulin resistance regardless of weight status

Key points Phentermine suppresses appetite short-term, and semaglutide works long-term Semaglutide achieves an average of 15%-20% weight loss versus phentermine's 5-10% Phentermine acts fast but has heart risks, and semaglutide has digestive side effects Both need diet and lifestyle changes to work effectively When you're in your doctor's office discussing weight loss medications, two names may come up: phentermine and semaglutide