Frontiers
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It's a significant, sometimes dramatic, shift
J Biol Chem (2011) 286(6):40819.10.1074/jbc.M110.134106 125 PouyssegurJShiuRPPastanI
[PubMed ID: 25653927]
However, the oncological significance of GCG signaling remains insufficiently defined, and the currently available evidence does not support a uniform conclusion that GCGR activation exerts a direct antitumor effect (61)
Data availability Data sharing is not applicable to this article as no new data were created or analyzed in this study
