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[DOI] [PMC free article] [PubMed] [Google Scholar] 99.Castaneda D, et al

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Antipsychotic-like effect of GLP-1 agonist liraglutide but not DPP-IV inhibitor sitagliptin in mouse model for psychosis

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For example, investigators found that orexigenic effects of systemically administered ghrelin (also known as the hunger hormone) were abolished in CB 1 receptor knockout mice 40 , and pharmacological blockade of the CB 1 receptor, via rimonabant administration, attenuated ghrelin-induced activation of the mesolimbic dopamine system a key pathway involved in reward processing 41

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The FDA has taken tirzepatide off the drug shortage list

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The remarkable weight loss results from GLP-1 receptor agonists have led doctors to prescribe them widely for obesity management

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