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Also, Frssing et al
With expanded coverage, the researchers predicted that incremental Medicare drug costs would total nearly $66 billion over 10 years, with only $18 billion saved through reduced hospitalizations and chronic disease care, leading to a net total of $48 billion in new spending
Zanoveli JM, Morais HD, Dias IC, Schreiber AK, Souza CP, Cunha JM

The half-life of TZT is 5 days, the expected steady state is 45 weeks, body clearance is 0.028 L/h, and the volume of distribution is 5.27L

Curr Med Res Opin 2010
