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This intervention was accompanied by a decrease in preference for low-dose sucrose solutions (0.1 M) (Zhang et al., 2013)

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Cummings: Between semaglutide and tirzepatide, tirzepatide is a little stronger on the usual (clinical trial) endpoints

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Thyroid Tumors: Animal studies suggest a potential risk for certain thyroid tumors, though the relevance to humans is still under investigation

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Both drugs share a similar side-effect pattern: nausea, vomiting, diarrhea, and constipation are the most common issues , usually mild to moderate and dose-related though it appears fewer people stop taking tirzepatide due to side effects

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This becomes even more important during the maintenance phase because patients need enough strength, protein, and activity to live comfortably at their new weight

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