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This intervention was accompanied by a decrease in preference for low-dose sucrose solutions (0.1 M) (Zhang et al., 2013)

Cummings: Between semaglutide and tirzepatide, tirzepatide is a little stronger on the usual (clinical trial) endpoints

Thyroid Tumors: Animal studies suggest a potential risk for certain thyroid tumors, though the relevance to humans is still under investigation

Both drugs share a similar side-effect pattern: nausea, vomiting, diarrhea, and constipation are the most common issues , usually mild to moderate and dose-related though it appears fewer people stop taking tirzepatide due to side effects

This becomes even more important during the maintenance phase because patients need enough strength, protein, and activity to live comfortably at their new weight
