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Description
5.3 Diabetic Retinopathy Complications In a pooled analysis of glycemic control trials, patients reported diabetic retinopathy related adverse reactions during the trial (4.2% with semaglutide tablets and 3.8% with comparator) [see Adverse Reactions (6.1)]

These results are not surprising, given that the role of semaglutide and other GLP-1 analogues in reducing appetite, calorie intake, and consummatory behaviors has been well documented factors that contributed to semaglutides approval for the treatment of obesity (69)

Overall, their findings proved the sympathetic inhibition via CNS of SGLT-2i
A retatrutide dose is still active seven days later, and tirzepatide is similar

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