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In preclinical research models, the timeline for metabolic response will depend on species, dose, and the specific endpoints being measured

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As part of our commitment to effective treatment, we offer guidance on injectable medications like Ozempic and tirzepatide, both of which are at the forefront of diabetes management

The pathophysiology of diabetic nephropathy is mainly due to the enhanced glucose uptake in tubule cells via SGLT2 inducing oxidative stress, expression of inflammatory and fibrosis genes, and increased apoptosis (Figure 2) [85,86]
