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Furthermore, in a more physiological setting, CCK-1R antagonism during a fasting-refeeding paradigm results in hyperglycemia, highlighting the glucoregulatory relevance of CCK-8 signaling 194

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Subgroup analysis showed overlapping effect estimates for the 5 mg, 10 mg, 15 mg, and MTD groups, with no significant difference observed between dose levels (p-value for subgroup differences = 0.56)

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Although variable, edema often resolves within six to 11 weeks

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