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Description
The EM structure of Tirzepatide bound to the complete GLP-1R and G-proteins (Figure 2, PDB ID 7rgp , Sun et al., 2022) shows some hydrophobic and some specific polar interactions between the peptidic drug and the GLP-1 receptor molecule

32(suppl_2)

[DOI] [PMC free article] [PubMed] [Google Scholar] 119.Takahashi Y., Nomoto H., Yokoyama H., Takano Y., Nagai S., Tsuzuki A., Cho K.Y., Miya A., Kameda H., Takeuchi J., et al

GLP-1 microdosers are chasing longevity

The press release highlights the companys partnership with a leading US manufacturer of generic and 503B compounded injectable medications
