glp-1 stock market Receptor Agonist Size, Share GLP-1 Agonists Market Report 2025-2033,

Certain groups already face higher baseline risk for NAION, regardless of GLP-1 use: Adults over age 50

Brainstem BDNF neurons are downstream of GFRAL/GLP1R signalling

The question is whether that system is being supported well

14,15 Potential Direct Effects on the Heart Although the systemic indirect effects of GLP-1RAs are well established as the primary drivers of their clinical benefit in HF, emerging preclinical and mechanistic evidence suggests GLP-1RAs may also exert some direct cardioprotective effects, as discussed below

If sleep disturbances are troubling, it is worth reviewing all medications and lifestyle factors with your healthcare provider