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[DOI] [PubMed] [Google Scholar] 43.Husain M., Birkenfeld A.L., Donsmark M., et al

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Two Molecules, Same Target# Weight Loss Data# *PA = placebo-adjusted Cross-trial caveat: Aleniglipron's data is Phase 2b (smaller, shorter) while orforglipron has Phase 3 data (larger, longer)

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Standard Eligibility Criteria for Semaglutide Weight Loss The FDA approved semaglutide for chronic weight management in individuals with a body mass index (BMI) of 30 or higher, or those with a BMI of 27 or above who also have at least one weight-related condition such as high blood pressure, type 2 diabetes, or heart disease