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The primary outcome for LEADER, SUSTAIN-6, EXSCEL, HARMONY Outcomes, REWIND, PIONEER 6 and AMPLITUDE-O was a three-point MACE, whereas ELIXA used a four-point MACE, including also hospital admission for unstable angina

In the results of the study, obesity model mice showed abnormalities in lipid metabolism, manifested by high TC, TG, LDL-C and HDL-C

1065 With respect to pilots with DM, recent experience in Europe reported no episodes of pilot incapacitation nor worsening of glycemic control with insulin-treated DM