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Description
Retatrutide Phase 2: 17.5% body weight NEJM 2023 Cardiovascular Metabolic Cardio-Metabolic Research GLP-1 class reduces cardiovascular events

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The concern stems from MOTS-c's effects on cellular proliferation and metabolism
Normal side effects like mild nausea typically improve within a few weeks of starting treatment, while gastroparesis involves persistent symptoms that may worsen over time

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