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In the CRL, the FDA said Alnylam had not provided enough evidence of the therapys benefit

doi: 10.2337/dc15-1643 361 LargerEWewer AlbrechtsenNJHansenLHGellingRWCapeauJDeaconCFet al

Zepbound is the first and only approved treatment activating two incretin hormone receptors, GIP and GLP-1, to tackle an underlying cause of excess weight, according to Lillys announcement

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Their origins as diabetes medicines, however, provide a medical foundation that has made prescribing them relatively less burdensome